Hapless museum night watchman Larry Daley must help his living, breathing exhibit friends out of a pickle now that they've been transferred to the archives at the Smithsonian Institution. Larry's (mis)adventures this time include close encounters with Amelia Earhart, Abe Lincoln and Ivan the Terrible.

When a comet passes close to the earth, machines all over the world come alive and go on homicidal rampages. A group of people at a desolate truck stop are held hostage by a gang of homicidal 18-wheelers. The frightened people set out to defeat the killer machines ... or be killed by them.

Geeky student Arnie Cunningham falls for Christine, a rusty 1958 Plymouth Fury, and becomes obsessed with restoring the classic automobile to her former glory. As the car changes, so does Arnie, whose newfound confidence turns to arrogance behind the wheel of his exotic beauty. Arnie's girlfriend Leigh and best friend Dennis reach out to him, only to be met by a Fury like no other.